Dietitian CE

Hesperidin and Caffeine Elicits an Anti-Obesity Effect

1. The mechanism of the TG-lowering effect of G-hesperidin is thought to be due to which of the following?

A. Down-regulation of the synthesis/secretion of very-low-density lipoprotein in hepatocytes. B. Inhibition of lipogenesis. C. Induction of beta oxidation of fatty acids in high-fat diets. D. All of the above.

2. Caffeine has been reported to induce all of the following in humans, except:

A. Lipolysis of adipocytes B. Body fat reduction C. Fat oxidation D. Energy expenditure

3. A mixture of thiamine, L-arginine, caffeine, and citric acid has been shown to have an anti-obesity effect in humans with a high BMI.

A. True B. False

4. A combination of G-hesperidin and caffeine reduces accumulation of body fat through inhibition of:

A. Hepatic lipogenesis B. Adipocyte lipogenesis C. Muscle lipogenesis D. All of the above

5. All of the following groups were found to have decreases in total fat area significantly greater than those in the placebo group, except for:

A. 500-mg G-hesperidin with 25-mg caffeine B. 500-mg G-hesperidin with 50-mg caffeine C. 500-mg G-hesperidin with 75-mg caffeine D. All of the above were found to be significant

6. Degree of decrease of total fat area appeared to be enhanced in a caffeine dose-dependent manner.

A. True B. False

7. There were no significant decreases between the placebo group and groups that ingested G-hesperidin with or without caffeine in which of the following?

A. Total fat area B. Subcutaneous fat area C. Visceral fat area D. None of the above

8. Decreases in the BMI in the G-hesperidin with 75-mg caffeine group were significantly greater than those in the placebo group at:

A. Week 8 B. Week 12 C. Both week 8 and week 12 D. None of the above

9. Significant decreases in all of the following were observed in the G-hesperidin with 75-mg caffeine group compared with those in the placebo group, except for:

A. Body weight B. Hip circumference C. BMI D. Significant decreases were observed in all of the above

10. Concomitant and habitual intake of caffeine with G-hesperidin is required for the anti-obesity activity of this combination.

A. True B. False


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