Glucose Control Associations with Muscle and Resveratrol

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Commission on Dietetic Registration (CDR) - Provider #21328, Activity #158846 approved for 2 CPEUs.

CPEU Course Description

Individuals with obesity are at a higher risk for obesity-associated medical conditions, such as metabolic syndrome, and insulin resistance, which can develop into type 2 diabetes mellitus.  Musclin is a novel skeletal muscle-derived secretory factor considered to be a potent regulator of glucose metabolism and therefore may contribute to the pathogenesis of obesity and insulin resistance.  Resveratrol is an antioxidant that has shown potential benefit in those with T2DM.  This CPEU course examines the plasma musclin levels in overweight / obese subjects and lean controls and assesses the effects of resveratrol on glycemic control and insulin sensitivity among patients with T2DM.

Brooke H. Dekofsky, MPH, RD, CLE, CDE was involved in the creation of this course.

Article Author:  Yue Liu, MD, PhD, et al.

Exam writer: Tiev LaGuire, M.S.

CPEU Course Objectives

1. Conclude in which tissue musclin has been found to be almost exclusively expressed.
2. Describe the type of factor that musclin has been shown to be in animal models.
3. Explain the difference between plasma musclin levels in subjects with obesity compared to lean controls.
4. Identify the daily dose of resveratrol needed for significant improvements to be found.
5. List five measures for which resveratrol supplementation for T2DM resulted in significant and clinically relevant changes.
6. Provide the mechanism for how musclin impaires insulin-induced glucose uptake.

This course expires on 10/28/2023

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CPE Level: II

Learning Codes: 2010, 2100, 5190, 5370

Performance Indicators (RDN): 6.2.5, 8.1, 8.1.2 , 8.3.6

Performance Indicators (NTDR): 6.2.5, 8.1, 8.1.2 , 8.3.6

Course Date: 2019-07-02

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