Folate and Alcohol Influences on Leukocyte DNA Methylation

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How to Take This Course:

• 1 View Course Worksheet -  View the course worksheet or print it out to review later
• 2 Read the Course Material -  As you read through, mark your answers on the course worksheet to be prepared for the exam
• 3 Take Exam -  You must achieve a score of 70% or higher in order to earn credit for the course.
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Course Description

Commission on Dietetic Registration (CDR) - Provider #21328, Activity #164354 approved for 1.50 CPEUs.

CPEU Course Description

There is increasing evidence that folate, an important component of one-carbon metabolism, modulates the epigenome.  Alcohol, which can disrupt folate absorption, is also known to affect the epigenome.  This CPEU course investigates the association of dietary folate and alcohol intake on leukocyte DNA methylation levels.

An RD was involved in the creation of this course.
Article Author:  Vivian Viallon, Ph.D., et al.
Exam writer: Tiev LaGuire, M.S.

CPEU Course Objectives

1.  Analyze the genes and diseases for which alcohol consumption was positively and inversely associated with methylation.

2.  Describe the characteristics of DNA methylation.

3.  Illustrate how ethanol metabolism generates toxins that may directly lead to one-carbon metabolism dysfunction.

4.  Summarize how dietary folate has an influence with the Rho signal transduction pathway and the three forms of associated cancer.

This course expires on 07/01/2024

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CPE Level: II

Learning Codes: 2060, 2090, 2100, 5150

Performance Indicators (RDN): 6.2.5, 8.1, 8.1.3 , 8.1.5

Performance Indicators (NTDR): 6.2.5, 8.1, 8.1.3 , 8.3.6

Course Date: 2019-07-30

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